Cell-Logic EnduraCell® Plus

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Cell-Logic EnduraCell® Plus

The unique phytonutrients contained in broccoli sprouts may activate the body’s natural cellular detoxification processes and antioxidant defences. Scientific research indicates that selenium (an essential trace element in human nutrition) supports antioxidant activity in the body. When taken as directed, this product assists in the maintenance and improvement of general well being.

Product Details

The EnduraCell® Plus formulation is based on the same grade and quantity of EnduraCell® but with the addition of 25 mcg selenium per capsule. Many of the enzymes which increase cellular defences, depend upon seleno-enzymes.

Features

EnduraCell® Plus may:

• Stimulate cellular antioxidant defences within the body
• Activate key enzymes in liver detoxification
• Support selenium deficient diets
• Aid thyroid metabolism and protection
• Support gut homeostasis and immune function

Ingredients

Each size ’00’ capsule contains:

• EnduraCell® 100% Whole Broccoli Sprout Powder (Brassica oleracea var. italica sprout powder): 700mg
• Selenomethionine: 62.5mcg (Eqv. 25 mcg selenium)

NOTE: Cell-Logic EnduraCell® is hydroganically grown in a carefully controlled environment to maximise bioactivity. Our hydroganic growing process does not use any herbicides, pesticides or other harmful chemicals. EnduraCell® Plus is GMO free and does not contain goitrogens or significant levels of Vitamin K.

Applications

Recommended Daily Dosage: Adults take 1– 2 capsules twice daily, or as directed by your Health Care Practitioner.

Do not exceed 6 capsules daily.

Warnings

This product contains selenium which is toxic in high doses. For adults, a daily dose of 150 micrograms of selenium from dietary supplements should not be exceeded.

Store below 30°C away from light and moisture.

Do not exceed 6 capsules daily.

Very occasionally, gastro-intestinal adverse effects have been reported, and include nausea, gastro-abdominal discomfort and diarrhoea. Limited data available seem to indicate that such effects are limited to certain pre-existing gastro-intestinal conditions, in particular, those with dysbiosis. However, it has been observed that for those affected, the dose can be managed in a manner whereby the symptoms disappear and may not recur even after the consumption of larger doses.

Evidence

Li D et al. Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes Food Chemistry 110 (2008) 193–198

Lee J-M, Johnson JA. An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism Journal of Biochemistry and Molecular Biology 2004 ; 37(2):139-143

Fahey JW, Talalay P. Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes. Food and Chemical Toxicology. 1999; 37:973-979

Fahey JW, Kensler TW. Role of dietary supplements/nutraceuticals in chemoprevention through induction of cytoprotective enzymes. Chem Res Toxicol. 2007 Apr;20(4):572-6.

Yeh C-T, Yen G-C. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005;26 (12) ;2138–2148

Jeong W-S et al. Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway. Pharmaceutical Research. 2004;21(4): 661-670.

Innmorato NG et al. The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation. The Journal of Immunology 2008;181:680 – 689.

Wu L, Juurlink B The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of Hypertension 2001, 19:181-1825

Cramer J, Jeffery EH. Sulforaphane Absorption and Excretion Following Ingestion of a Semi-Purified Broccoli Powder Rich in Glucoraphanin and Broccoli Sprouts in Healthy Men.2011; Nutrition and Cancer, 63(2), 196–201

Halliwell B Free radicals and antioxidants – quo vadis? Trends in Pharmacological Sciences 2011: 32(3):125-130.

Kensler TW et al. Translational Strategies for cancer prevention in liver. Nature Reviews Cancer 3, 321-329 (May 2003)

2001 Steinkellner H et al. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutation Research 480–481